Chosen Solution

Does anyone know if this video card will work on the MacPo 2006 upgraded to 3.0GHz, 32GB Ram flashed to 2.1, OS X 10.5.7?

It should work, since it’s just a graphics card. Honestly, give it a shot! If it doesn’t work, you can keep working on fixing it, or just sell the graphics card! Maybe also try getting something more oomph-ier, if you’re going to be using dedicated graphics. Good luck!

Unless this card has been flashed for a Mac, it will not work.